Search results for "Disseminated disease"

showing 3 items of 3 documents

Prognostic Factors in Childhood Anaplastic Large Cell Lymphoma: Long Term Results of the International ALCL99 Trial

2020

With the aim of describing the long-term follow-up and to define the prognostic role of the clinical/pathological/molecular characteristics at diagnosis for childhood, adolescent and young adults affected by anaplastic large cell lymphoma (ALCL), we analyzed 420 patients aged up to 22 years homogeneously treated within the international ALCL99 trial. The 10-year progression free survival (PFS) was 70% and overall survival was 90%, rare late relapses occurred but no secondary malignancies were reported. Among clinical/pathological characteristics, only patients presenting a small cell/lymphohistiocytic (SC/LH) pattern were independently associated with risk of failure (hazard ratio = 2.49). …

MDD0301 basic medicineOncologyCancer Researchmedicine.medical_specialtyMultivariate analysisIMPACTBONE-MARROWFEATURESCHILDRENlong-term follow-uplcsh:RC254-282ArticleDISEASECLASSIFICATIONChildhood Anaplastic Large Cell Lymphoma03 medical and health sciences0302 clinical medicineInternal medicineADOLESCENTSmedicineVINBLASTINEProgression-free survivalYoung adultPathologicalAnaplastic large-cell lymphomachildhoodScience & Technologybusiness.industryHazard ratioCHEMOTHERAPYlcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogensmedicine.diseaseALCLALCL; MDD; childhood; long-term follow-up030104 developmental biologyOncology030220 oncology & carcinogenesisMinimal Disseminated DiseaseNON-HODGKIN-LYMPHOMAbusinessLife Sciences & BiomedicineCancers
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Molecular epidemiology and whole genome sequencing analysis of clinical Mycobacterium bovis from Ghana

2019

[Background]: Bovine tuberculosis (bTB) caused by Mycobacterium bovis is a re-emerging problem in both livestock and humans. The association of some M. bovis strains with hyper-virulence, MDR-TB and disseminated disease makes it imperative to understand the biology of the pathogen.

MaleBacterial Diseases0301 basic medicineBovine Tuberculosis in HumansHIV InfectionsComorbidityDrug resistanceGhanaBiochemistryMycobacterium BovisGeographical LocationsZoonosesMedicine and Health SciencesDisseminated diseaseBovine TuberculosisChildPathogenPhylogenyMolecular Epidemiology0303 health sciencesMycobacterium bovisMultidisciplinaryTransmission (medicine)QRAgricultureMiddle AgedLipids3. Good healthActinobacteriaInfectious DiseasesMedicineFemaleResearch ArticleAdultDNA BacterialLivestockTuberculosisAdolescentScience030106 microbiologyBiologyMycobacterium tuberculosisYoung Adult03 medical and health sciencesDrug Resistance BacterialmedicineAnimalsHumansTuberculosisTuberculosis PulmonaryAged030304 developmental biologyWhole genome sequencingWhole Genome SequencingBacteriaMolecular epidemiology030306 microbiologyOrganismsBiology and Life SciencesTropical DiseasesLipid MetabolismrpoBmedicine.diseasebiology.organism_classificationVirologyMetabolism030104 developmental biologyMutationPeople and PlacesAfricaCattleTuberculosis BovineMycobacterium Tuberculosis
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Linfoma no-hodgkin intraoral. presentación de 4 casos clínicos

2001

The non-Hodgkin lymphomas (NHL) represent an heterogeneous group of malignancies of lymphoreticular histogenesis. In most cases, they initially arise within lymph nodes but so-called extranodal lymphomas are also found. The NHL has low incidence in the oral cavity. It may involve bone and/or soft tissues as a primary or secondary manifestation. We present a review of the literature and four clinical cases of intraoral NHL. The first couple of cases are primary forms, the third one is associated to HIV infection and the last one is an oral presentation as a component of more widely disseminated disease.

Mouth neoplasmmedicine.medical_specialtybusiness.industryIncidence (epidemiology)Soft tissueHistogenesismedicine.diseaseDermatologyLymphomaOtorhinolaryngologyimmune system diseaseshemic and lymphatic diseasesmedicineDisseminated diseaseLymphbusinessExtranodal lymphomasActa Otorrinolaringológica Española
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